We are pleased to highlight a newly published study in the July issue of Movement Disorders:
Full citation:
Andreoli L, Nyman T, Espa E, Jakobsson J, Elabi OF, and Cenci MA. Indirect Striatal Projection Neurons Drive a D2 Receptor-Dependent Pathway to Dyskinesia and Dystonia. Movement Disorders. 2026;41(7):1690–1703. https://doi.org/10.1002/mds.70299
This new study demonstrates (for the first time) that the activity of D2 receptors on indirect-pathway striatal neurons plays a causal role in L-DOPA-induced dyskinesias!
